HIV in Children

TREATMENT OF HERPES ZOSTER

Dr. Ira Shah
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Last Updated : 1st September 2012

Drugs

Dosage

Adverse Effects

Remarks
Acyclovir Severe immunosuppression,
Trigeminal nerve
involvement or
Multidermatomal zoster:
10 mg/kg/dose IV tds for
7-14 days Mild disease:
20 mg/kg/dose tds PO for
7-10 days
Renal toxicity, Phlebitis, nausea, vomiting, rash, neutropenia Drug of choice for chickenpox
Foscarnet 120 mg/kg/day IV in 3
divided doses for 7 days
Renal toxicity, electrolyte
imbalance including
abnormalities in calcium,
phosphorus, magnesium and
potassium, seizures, cardiac
arrhythmia's, elevated liver
enzymes, CNS symptoms
Useful in acyclovir resistant chickenpox
Valacyclovir 1 gm PO BD for 7-10 days in adolescents Renal toxicity - other side
effects as of acyclovir. Nausea,
Vomiting, thrombotic Microangiopathy
Limited data in children

TREATMENT OF HERPES ZOSTER
Dr. Ira Shah
Incharge Pediatric HIV and TB Clinic, B.J.Wadia Hospital for Children, Mumbai, India Consultant in Pediatric Infectious Diseases, Nanavati Hospital, Mumbai, India.