HIV in Children
GRAND ROUNDS AND TEACHING FILES
HIV and Burkitt’s Lymphoma
Ira Shah
Consultant in Pediatric Infectious Diseases and Pediatric Hepatology, Nanavati Hospital, Mumbai, India
Incharge, Pediatric HIV and TB Clinic, B J Wadia Hospital for Children, Mumbai, India

A 5 years old male child was diagnosed to have Burkitt’s Lymphoma (NHL) 15 days ago. On screening his Elisa was positive for HIV-1. Both parents were HIV negative. On examination, he had pallor and hepatosplenomegaly. His HIV infection was confirmed by Western blot. HIV viral load was 958000 copies/ml and CD4 count was 576 cells/cumm. He was started on chemotherapy of dexamethasone, prednisolone, cyclophosphamide and vincristine but was withheld after the HIV report came positive. He was thus referred for his HIV treatment.

How should this child be treated?
See Previous Teaching Files