ISSN 0973 - 9289

June 2019 NEWSLETTER

Newsletter

2019

June

June 2019 Newsletter

GRAND ROUNDS

A 6 years old HIV infected boy presented with intermittent cough for 2 years. His mother had died of AIDS and pulmonary TB 2 years ago. On examination, the child was malnourished (weight = 12 kg, height = 98 cm), had bilateral crepitations and hepato- splenomegaly. Investigations showed:
• Hemoglobin = 9.8 gm/dl
• WBC count = 4,700/cumm [66% polymorphs, 32% lymphocytes]
• ESR = 57 mm of Hg
• SGPT = 90 IU/L
• SGOT = 115 IU/L
• Amylase = 37 IU/L
• Chest X-Ray = Left lower zone haziness
• USG Abdomen = Hepatosplenomegaly with fatty liver.
• CD4 count = 349 (18.5%)
• HBsAg, HCV = Negative

He was treated with antibiotics and pneumonia responded. He was then put on 3 drugs antiretroviral therapy (ART) consisting of abacavir (ABC), lamivudine (3TC) and efavirenz (EFV). After 2 months, his weight was the same and SGPT was 105 IU/L, albumin, bilirubin and prothrombin time was normal. After another month, he was admitted with severe metabolic acidosis and pulmonary bleed and died due to the same.

What was the cause of liver disease in this child?

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HIV GRAND ROUNDS

A 32 years old HIV infected pregnant female (G2P2L1) presented at 36 weeks of pregnancy for deciding neonatal antiretroviral (ARV) prophylaxis. Her HIV viral load at 34 weeks of gestation was undetectable and she was on antiretroviral therapy (ART) consisting ....

HIV IN CHILDREN APPS