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June 2014 NEWSLETTER

HIV IN CHILDREN
June 2014 Newsletter
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An 11 years old HIV infected boy was referred for HIV management. He has been treated for tuberculosis (TB) 1½ years ago for 9 months with anti TB treatment (ATT). On examination, he had generalized lymphadenopathy, papular dermatitis, bilateral crepts in both lungs and hepatosplenomegaly. Chest X-Ray showed left lower zone haziness that was persisting for the past 1½ years. His CD4 count was 157 cells/cumm. He was suspected to have drug resistant (DR) TB and started on category 2 of ATT and sputum was sent for TB culture. There was no growth of mycobacteria even after 6 weeks. At end of 6 weeks, he was also started on antiretroviral therapy (ART) consisting of zidovudine (AZT), lamivudine (3TC) and efavirenz (EFV). Inspite of category 2 ATT for 4 months and ART, there was no improvement in chest X-Ray, infact the haziness had increased. The child however had put on 5 kg in these past 4 months and had developed clubbing and parotid enlargement and continued to have fine crepts.

What is the cause of his respiratory problems?

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