ISSN 0973 - 9289

January 2017 NEWSLETTER

Newsletter

2017

January

January 2017 Newsletter

GRAND ROUNDS

A 10 years old HIV infected girl was referred for further management. The child had abdominal distension for past one month and ultrasonography (USG) of the abdomen showed mild hepatomegaly & splenomegaly with ascites. Investigations showed hemoglobin of 11 gm/dl, white cell count of 3,900/cumm (52% polymorphs, 40% lymphocytes) and ESR of 100 mm at end of 1 hour. Liver function tests (LFT) were abnormal and serial LFT over next 6 months are depicted in Table 1. CD4 count was 129/cumm. HBsAg, Hepatitis C ELISA, ANA, Anti liver kidney microsomal (Anti LKM) antibody and anti smooth muscle antibody were negative. Her 24 hours urine copper was 30.24 µg/day and ophthalmological examination was normal. Serum alpha 1 antitrypsin was 1.63 g/L (Normal = 0.9-2 g/L). In view of no other cause of hepatitis being detected, she was started on antiretroviral therapy (ART) consisting of Zidovudine (AZT), Lamivudine (3TC) and Efavirenz (EFV). Three months later, her liver enzymes gradually decreased (SGOT = 82 IU/L, SGPT = 63 IU/L).

How is it possible that older child is HIV positive and younger child is HIV negative?

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HIV GRAND ROUNDS

A 32 years old HIV infected pregnant female (G2P2L1) presented at 36 weeks of pregnancy for deciding neonatal antiretroviral (ARV) prophylaxis. Her HIV viral load at 34 weeks of gestation was undetectable and she was on antiretroviral therapy (ART) consisting ....

HIV IN CHILDREN APPS