ISSN 0973 - 9289

April 2016 NEWSLETTER

HIV IN CHILDREN
April 2016 Newsletter
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GRAND ROUNDS
A 5 years old HIV infected boy was diagnosed as having pulmonary tuberculosis 2 months ago and was on antituberculous therapy (ATT). Investigations showed anemia with thrombocytopenia. Echocardiography showed left ventricular hypertrophy with dilatation with normal ejection fraction (62%) suggestive of HIV cardiomyopathy. He was started on 3 drug ART. Four months after starting ART, his weight had increased by 1 kg and height by 6 cm and platelet count increased to 1,20,000/cumm. Thus, this child’s anemia and thrombocytopenia improved with antiretroviral therapy.

What is the cause of thrombocytopenia in this child?

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Question Of the Day
I have an 8 years old child diagnosed HIV at 3 years age, on ABC, 3TC, NVP. He developed jaundice and meds were stopped. After that given EFV instead of NVP, mum reports jaundice on that regimen and drugs have been stopped and restarted on the same. Currently comes with fever, hepatosplenomegally, generalized lymphadenopathy and finger clubbing. Ultrasound shows splenic abscesses- the child is on vancomycin, metronidazole but still spiking high fevers of 40 degrees. We started on 2nd line HAART regime AZT, 3TC, LPV/r. CXR and CT chest showed no evidence of TB, gene xpert negative. Please advise on what else i should do?
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